protein

RPS20PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPS20PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

The ribosomal machinery is fundamental to cellular protein homeostasis (proteostasis).

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🔬 Protein Info

Gene Symbol	RPS20PROTEIN
Chromosome	8q12.1
Function	is a component of the 40S small ribosomal subunit in eukaryotic cells.
Subcellular Localization	</th><td>Cytoplasm, ribosome</td></tr>
GeneCards	RPS20PROTEIN
Human Protein Atlas	RPS20PROTEIN
Basic residues	RPS20 contains multiple lysine and arginine residues that facilitate binding to the 18S rRNA of the 40S subunit
Platform region location	RPS20 is located on the platform region of the 40S subunit, where it contributes to the structural integrity of the mRNA binding channel
Compact fold	The protein has a compact, globular fold typical of many small ribosomal proteins
mRNA interaction	RPS20 contributes to stabilizing interactions between the 40S subunit and mRNA molecules during translation initiation
mRNA binding	RPS20 contributes to stabilizing the binding of mRNA to the 40S subunit
Scanning mechanism	The protein participates in the scanning mechanism that locates the start codon on the mRNA
Translation initiation complex	RPS20 is involved in the formation of the 48S translation initiation complex
Ribosome assembly	The protein participates in the assembly of the 40S subunit, integrating with 18S rRNA and other ribosomal proteins
Early assembly	RPS20 is incorporated into the 40S subunit during early stages of assembly
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Ribosomal Protein S20

protein · 984 words

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Pathway Diagram

graph TD
    RPS20PROTEIN["RPS20PROTEIN"]
    neurodegeneration["neurodegeneration"]
    RPS20PROTEIN -->|"implicated_in"| neurodegeneration
    style RPS20PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

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Related Research

Hypotheses and analyses mentioning RPS20PROTEIN in their description or question text

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