Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPS27L: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RPS27L |
| Full Name | Ribosomal Protein S27 Like |
| Chromosome | 15q21.3. |
| Function | is a member of the ribosomal protein S27 family that plays essential roles in protein synthesis as a component of the 40S ribosomal subunit. |
| Primary Expression | most tissues with particularly high levels in the brain, where it participates in neuronal protein synthesis essential for synaptic plasticity and neu |
| Subcellular Localization | both the soma and dendritic compartments, where it supports local protein synthesis at synapses |
| Molecular Weight | 11 kDa |
| Amino Acids | 103 aa |
| Exons | 5 |
| UniProt ID | Q9GZL0 |
| NCBI Gene ID | 51065 |
| Ensembl ID | ENSG00000149691 |
| OMIM | 618199 |
| GeneCards | RPS27L |
| Human Protein Atlas | RPS27L |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
RPS27L["RPS27L"]
neurodegeneration["neurodegeneration"]
RPS27L -->|"implicated_in"| neurodegeneration
style RPS27L fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RPS27L in their description or question text
No additional research found