gene

SCYL1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SCYL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	SCYL1
Protein Type	Kinase
Function	SCYL1 is a member of the SCY1-like family characterized by a pseudokinase domain lacking catalytic activity. The protein contains multiple domains including:
Subcellular Localization	to the Golgi apparatus and cytosol
GeneCards	SCYL1
Human Protein Atlas	SCYL1
N-terminal HEAT repeats	Involved in protein-protein interactions and intracellular trafficking
Pseudokinase domain	May function as a scaffolding protein
C-terminal region	Contains binding sites for various trafficking proteins
Cerebellar ataxia	Progressive loss of coordination
Peripheral neuropathy	Sensory and motor deficits
Developmental delay	Particularly in speech and motor milestones
Spasticity	Upper motor neuron involvement
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

SCYL1 Gene

gene · 577 words

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Genes

index · 271 words

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Pathway Diagram

graph TD
    SCYL1["SCYL1"]
    neurodegeneration["neurodegeneration"]
    SCYL1 -->|"implicated_in"| neurodegeneration
    style SCYL1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity