gene

SEPT4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SEPT4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	SEPT4
Full Name	Septin 4
Chromosome	17q23.2
Function	encodes a neuronally-enriched member of the septin family of GTP-binding proteins with critical roles in synaptic function, apoptosis regulation, and neurodegenerative disease pathogenesis.
Primary Expression	dopaminergic neurons of the substantia nigra pars compacta
Molecular Weight	42.3 kDa
Amino Acids	377 aa
Exons	11
UniProt ID	O43276
Ensembl ID	ENSG00000154027
OMIM	608680
GeneCards	SEPT4
Human Protein Atlas	SEPT4
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: SEPT4 — AlphaFold O43276 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SEPT4 — Septin 4

gene · 2044 words

→

Pathway Diagram

graph TD
    SEPT4["SEPT4"]
    neurodegeneration["neurodegeneration"]
    SEPT4 -->|"implicated_in"| neurodegeneration
    style SEPT4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SEPT4 in their description or question text

No additional research found