Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about SEPTIN11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | SEPTIN11 |
| Aliases | SEPT11, Septin-11 |
| Chromosome | 4p14 |
| Function | is a member of the septin family of GTP-binding proteins that play critical roles in cytoskeletal organization, membrane dynamics, and cell division. |
| Primary Expression | neurons and has been implicated in synaptic function, neuronal development, and potentially in neurodegenerative disease pathogen |
| Subcellular Localization | **Synaptic Vesicles**: Localizes to presynaptic terminals |
| Amino Acids | 493 aa |
| Gene Type | Protein coding |
| UniProt ID | Q9NVE5 |
| NCBI Gene ID | 83452 |
| OMIM | 607284 |
| GeneCards | SEPTIN11 |
| Human Protein Atlas | SEPTIN11 |
| Gene Name | Septin 11 |
| Protein Length | 493 amino acids |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SEPTIN11["SEPTIN11"]
neurodegeneration["neurodegeneration"]
SEPTIN11 -->|"implicated_in"| neurodegeneration
style SEPTIN11 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||