protein

SEPTIN4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SEPTIN4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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Summary

Page for SEPTIN4 Protein

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🔬 Protein Info

Gene Symbol	SEPTIN4
Full Name	Septin 4
Chromosome	17q23.1
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	SEPTIN4 exhibits distinctive subcellular distribution:
Molecular Weight	43 kDa
Pathways	TGF-β signaling, TGF-β Signaling, TGF-β
UniProt ID	O43291
GeneCards	SEPTIN4
Human Protein Atlas	SEPTIN4
Hetero-oligomeric complexes	SEPTIN4 assembles with other septins (SEPT1, SEPT2, SEPT3, SEPT5, SEPT6, SEPT7, SEPT8, SEPT9, SEPT10, SEPT11, SEPT12, SEPT14) into complexes
Filaments and bundles	These complexes can polymerize into filaments and higher-order bundles
Membrane association	SEPTIN4 localizes to membrane compartments, particularly Golgi and plasma membrane
Parkin	Interactions with E3 ubiquitin ligase parkin
Tubulin	SEPTIN4 can associate with microtubules
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: SEPTIN4 — AlphaFold O43291 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

Septin 4

gene · 813 words

→

SEPTIN4 Protein

protein · 726 words

→

Pathway Diagram

graph TD
    SEPTIN4["SEPTIN4"]
    neurodegeneration["neurodegeneration"]
    SEPTIN4 -->|"implicated_in"| neurodegeneration
    style SEPTIN4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SEPTIN4 in their description or question text

No additional research found