Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SERCA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | SERCA |
| Aliases | Sarco/Endoplasmic Reticulum Ca²⁺-ATPase |
| Function | SERCA (Sarco/Endoplasmic Reticulum Ca²⁺-ATPase) pumps calcium ions from the cytosol into the endoplasmic reticulum (ER), maintaining the steep calcium gradient essential for calcium signaling |
| Molecular Weight | 110 kDa |
| GeneCards | SERCA |
| Human Protein Atlas | SERCA |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
SERCA["SERCA"]
neurodegeneration["neurodegeneration"]
SERCA -->|"implicated_in"| neurodegeneration
style SERCA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||