gene

SGSM2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SGSM2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

Small G Protein Signaling Modulator 2 - RAB GTPase regulator in endosomal trafficking

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	SGSM2
Aliases	Small G Protein Signaling Modulator 2
Chromosome	17p12
Function	RAB GTPases act as molecular switches that alternate between an active GTP-bound state and an inactive GDP-bound state.
Molecular Weight	98 kDa
Amino Acids	875 aa
Ensembl ID	ENSG00000138448
GeneCards	SGSM2
Human Protein Atlas	SGSM2
RAB5	Controls early endosome formation, fusion, and cargo sorting
RAB7	Regulates late endosome maturation, transport, and lysosomal fusion
RAB11	Mediates receptor recycling from endosomes to plasma membrane
RAB9	Controls transport between late endosomes and trans-Golgi network
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SGSM2

gene · 1743 words

→

Pathway Diagram

graph TD
    SGSM2["SGSM2"]
    neurodegeneration["neurodegeneration"]
    SGSM2 -->|"implicated_in"| neurodegeneration
    style SGSM2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SGSM2 in their description or question text

No additional research found