Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC12A2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Page for SLC12A2 — Solute Carrier Family 12 Member 2 (Na-K-2Cl Co-transporter 2)
| Gene Symbol | SLC12A2 |
| Full Name | Solute Carrier Family 12 Member 1 (Na-K-2Cl Co-transporter 1) |
| Aliases | Na-K-2Cl Co-transporter 2 |
| Chromosome | 5q23 |
| Function | is a neurological condition caused by pathogenic variants in SLC12A2. |
| Primary Expression | neuronal cell bodies and projections, where it plays a fundamental role in regulating intracellular chloride concentrations that directly influence ne |
| UniProt ID | P55012 |
| NCBI Gene ID | 6558 |
| Ensembl ID | ENSG00000144659 |
| OMIM | 600840 |
| GeneCards | SLC12A2 |
| Human Protein Atlas | SLC12A2 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SLC12A2["SLC12A2"]
neurodegeneration["neurodegeneration"]
SLC12A2 -->|"implicated_in"| neurodegeneration
style SLC12A2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity