Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC15A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SLC15A1 |
| Full Name | Solute Carrier Family 15 Member 1 (Peptide Transporter 1) |
| Aliases | Peptide Transporter 1 |
| Chromosome | 13q33 |
| Protein Type | Transporter |
| Function | is a proton-coupled oligopeptide transporter that mediates the uptake of di- and tripeptides from the intestinal lumen and renal tubules[@liang2018]. |
| Primary Expression | the small intestine and kidney, lower levels of expression have been detected in various brain regions, including the [hippocampus](/brain-regions/hip |
| Amino Acids | 708 aa |
| UniProt ID | P46059 |
| NCBI Gene ID | 6564 |
| Ensembl ID | ENSG00000156795 |
| OMIM | 600544 |
| GeneCards | SLC15A1 |
| Human Protein Atlas | SLC15A1 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SLC15A1["SLC15A1"]
neurodegeneration["neurodegeneration"]
SLC15A1 -->|"implicated_in"| neurodegeneration
style SLC15A1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SLC15A1 in their description or question text
No additional research found