gene

SLC1A6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC1A6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

SLC1A6 Gene

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🧬 Gene Info

Gene Symbol	SLC1A6
Full Name	Solute Carrier Family 1 Member 6 (EAAT4)
Chromosome	19p13.12
Protein Type	Transporter
Function	The SLC1A6 gene encodes the excitatory amino acid transporter 4 (EAAT4), a member of the solute carrier family 1.
Subcellular Localization	the dendritic spines and extrasynaptic membranes, serving as a major glutamate clearance
UniProt ID	P22732
NCBI Gene ID	6512
Ensembl ID	ENSG00000105143
OMIM	133010
GeneCards	SLC1A6
Human Protein Atlas	SLC1A6
Encoded Protein	EAAT4
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC1A6 — AlphaFold P22732 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (5)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    SLC1A6["SLC1A6"]
    neurodegeneration["neurodegeneration"]
    SLC1A6 -->|"implicated_in"| neurodegeneration
    style SLC1A6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity