protein

SLC25A12

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about SLC25A12: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for SLC25A12 Protein

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🔬 Protein Info

Gene Symbol	SLC25A12
Full Name	Solute Carrier Family 25 Member 12 (Aralar1)
Chromosome	2q31.1
Function	SLC25A12 is a member of the mitochondrial carrier family (SLC25) that transports metabolites across the inner mitochondrial membrane.
Primary Expression	various brain regions with specific patterns of cellular localization
Molecular Weight	68 kDa
Amino Acids	680 aa
UniProt ID	Q9NPJ3
NCBI Gene ID	5104
Ensembl ID	ENSG00000107140
OMIM	603667
GeneCards	SLC25A12
Human Protein Atlas	SLC25A12
Aspartate/Glutamate Exchange	Exchanges mitochondrial aspartate for cytosolic glutamate
Malate-Aspartate Shuttle	Essential component of NADH shuttling
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC25A12 — AlphaFold Q9NPJ3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

SLC25A12 Gene

gene · 685 words

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SLC25A12 Protein

protein · 1703 words

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Pathway Diagram

graph TD
    SLC25A12["SLC25A12"]
    neurodegeneration["neurodegeneration"]
    SLC25A12 -->|"implicated_in"| neurodegeneration
    style SLC25A12 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning SLC25A12 in their description or question text

No additional research found