protein

SLC25A13

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about SLC25A13: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for SLC25A13 Protein

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🔬 Protein Info

Gene Symbol	SLC25A13
Full Name	Solute Carrier Family 25 Member 13 (Citarin/Aralar2)
Chromosome	7q21.3
Function	SLC25A13 is a calcium-dependent mitochondrial aspartate/glutamate carrier that functions in the malate-aspartate shuttle and supports various metabolic pathways including the urea cycle and gluconeoge
Molecular Weight	68 kDa
Amino Acids	680 aa
UniProt ID	Q9H0M0
NCBI Gene ID	5105
Ensembl ID	ENSG00000004864
OMIM	603709
GeneCards	SLC25A13
Human Protein Atlas	SLC25A13
Aspartate/Glutamate Exchange	Exchanges mitochondrial aspartate for cytosolic glutamate
Urea Cycle Support	Provides aspartate for citrulline synthesis
Gluconeogenesis	Supports metabolic pathways in liver
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC25A13 — AlphaFold Q9H0M0 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

SLC25A13 Gene

gene · 642 words

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SLC25A13 Protein

protein · 1245 words

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Pathway Diagram

graph TD
    SLC25A13["SLC25A13"]
    neurodegeneration["neurodegeneration"]
    SLC25A13 -->|"implicated_in"| neurodegeneration
    style SLC25A13 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning SLC25A13 in their description or question text

No additional research found