Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC25A13: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | SLC25A13 |
| Full Name | Solute Carrier Family 25 Member 13 (Citarin/Aralar2) |
| Chromosome | 7q21.3 |
| Function | SLC25A13 is a calcium-dependent mitochondrial aspartate/glutamate carrier that functions in the malate-aspartate shuttle and supports various metabolic pathways including the urea cycle and gluconeoge |
| Molecular Weight | 68 kDa |
| Amino Acids | 680 aa |
| UniProt ID | Q9H0M0 |
| NCBI Gene ID | 5105 |
| Ensembl ID | ENSG00000004864 |
| OMIM | 603709 |
| GeneCards | SLC25A13 |
| Human Protein Atlas | SLC25A13 |
| Approach | Status |
| Diet Modification | Standard of Care |
| Liver Transplantation | Curative |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SLC25A13["SLC25A13"]
neurodegeneration["neurodegeneration"]
SLC25A13 -->|"implicated_in"| neurodegeneration
style SLC25A13 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||