SLC25A13

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolSLC25A13
Namesolute carrier family 25 member 13
Typeprotein-coding
Sourcemygene

Summary

This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms hav

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