Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC30A6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SLC30A6 |
| Full Name | Solute Carrier Family 3 Member 0A6 (SLC30A6) |
| Chromosome | 12p13.31 |
| Protein Family | SLC30 (CDF) family |
| Protein Type | Transporter |
| Function | is a zinc efflux transporter belonging to the CDF (Cation Diffusion Facilitator) family. |
| Primary Expression | the brain and is localized to the Golgi apparatus and secretory vesicles, where it sequesters zinc into these compartments |
| Subcellular Localization | s. ZnT6 is primarily expressed in the brain and is localized to the Golgi apparatus and secretory vesicles, where it seq |
| Amino Acids | 376 aa |
| UniProt ID | Q6NXR1 |
| NCBI Gene ID | 28517 |
| Ensembl ID | ENSG00000138401 |
| OMIM | 607340 |
| GeneCards | SLC30A6 |
| Human Protein Atlas | SLC30A6 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SLC30A6["SLC30A6"]
neurodegeneration["neurodegeneration"]
SLC30A6 -->|"implicated_in"| neurodegeneration
style SLC30A6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SLC30A6 in their description or question text
No additional research found