Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC30A9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SLC30A9 |
| Full Name | Solute Carrier Family 3 Member 0A9 (SLC30A9) |
| Chromosome | 4q21 |
| Protein Type | Transporter |
| Function | ZnT9 functions as a mitochondrial zinc transporter with several critical functions |
| Subcellular Localization | the Golgi, ZnT9 is predominantly mitochondrial, where it plays essential roles in mitochondrial zinc homeostasis and fun |
| UniProt ID | Q6ZMP9 |
| NCBI Gene ID | 57151 |
| Ensembl ID | ENSG00000107140 |
| OMIM | 608332 |
| GeneCards | SLC30A9 |
| Human Protein Atlas | SLC30A9 |
| Mitochondrial zinc regulation | Controls zinc import into mitochondria, essential for mitochondrial function[@zhang2024] |
| Early embryonic development | SLC30A9 is essential for mammalian early embryonic development[@zhang2024] |
| Oxidative stress response | Loss of SLC30A9 increases sensitivity to oxidative stress[@borgmann2022] |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SLC30A9["SLC30A9"]
neurodegeneration["neurodegeneration"]
SLC30A9 -->|"implicated_in"| neurodegeneration
style SLC30A9 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SLC30A9 in their description or question text
No additional research found