gene

SLC33A1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about SLC33A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for SLC33A1 — Solute Carrier Family 3 Member 3A1 (SLC33A1)

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🧬 Gene Info

Gene Symbol	SLC33A1
Full Name	Solute Carrier Family 3 Member 3A1 (SLC33A1)
Chromosome	3q27
Function	is a central metabolic intermediate required for acetylation reactions, lipid synthesis, and energy metabolism.
Primary Expression	various tissues with high expression in:
UniProt ID	O15297
NCBI Gene ID	9197
Ensembl ID	ENSG00000116497
OMIM	603690
GeneCards	SLC33A1
Human Protein Atlas	SLC33A1
Protein acetylation	Acetyl-CoA is the acetyl donor for N-acetyltransferases
Lipid biosynthesis	Acetyl-CoA is the precursor for fatty acid and cholesterol synthesis
Glycolipid metabolism	Important for myelin and neuronal membrane maintenance [@acetylcoab]
Brain	Neurons, particularly in regions with high metabolic activity
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC33A1 — AlphaFold O15297 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SLC33A1 — Solute Carrier Family 3 Member 3A1 (SLC33A1)

gene · 744 words

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Pathway Diagram

graph TD
    SLC33A1["SLC33A1"]
    neurodegeneration["neurodegeneration"]
    SLC33A1 -->|"implicated_in"| neurodegeneration
    style SLC33A1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity