Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC6A9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | SLC6A9 |
| Aliases | Glycine Transporter 2 |
| Chromosome | 1p34.1 |
| Function | The SLC6A9 locus is on chromosome 1p34.1 and encodes a 12-transmembrane-domain protein of approximately 638 amino acids. |
| Primary Expression | presynaptic terminals of glycinergic neurons in the brainstem and spinal cord |
| Amino Acids | 638 aa |
| GeneCards | SLC6A9 |
| Human Protein Atlas | SLC6A9 |
| Variant Type | Phenotype |
| Missense (trafficking) | Moderate |
| Missense (transport) | Moderate |
| Nonsense/frameshift | Severe |
| Splicing | Variable |
| Feature | GlyT2 (SLC6A9) |
| Cellular location | Presynaptic neuron |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
SLC6A9["SLC6A9"]
neurodegeneration["neurodegeneration"]
SLC6A9 -->|"implicated_in"| neurodegeneration
style SLC6A9 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||