gene

SMAD9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SMAD9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

0Debates

Summary

Comprehensive gene profile for SMAD9, a BMP-specific SMAD transcription factor involved in bone morphogenetic protein signaling, neurogenesis, and neurodegenerative disease pathogenesis.

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🧬 Gene Info

Gene Symbol	SMAD9
Full Name	SMAD Family Member 9
Chromosome	13q14.11
Protein Type	Receptor
Function	BMP ligand binding to type I and type II receptor complex
Primary Expression	various tissues including brain, lung, heart, and skeletal muscle
Molecular Weight	52 kDa
Amino Acids	467 aa
UniProt ID	[O15118](https://www.uniprot.org/uniprot/O15118)
Ensembl ID	ENSG00000120798
OMIM	603295
GeneCards	SMAD9
Human Protein Atlas	SMAD9
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SMAD9 — SMAD Family Member 9

gene · 1740 words

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Pathway Diagram

graph TD
    SMAD9["SMAD9"]
    neurodegeneration["neurodegeneration"]
    SMAD9 -->|"implicated_in"| neurodegeneration
    style SMAD9 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SMAD9 in their description or question text

No additional research found