SMURF1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolSMURF1
NameSMAD specific E3 ubiquitin protein ligase 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2010].

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