| Symbol | LOC116158507 |
| Name | CRISPRi-validated cis-regulatory element chr4.2649 |
| Type | biological-region |
| Source | mygene |
This genomic region represents a DNase I hypersensitive site (DHS) that was predicted to be an enhancer by the ENCODE (ENCyclopedia Of DNA Elements) project based on various combinations of H3K27 acetylation and binding of p300, GATA1 and RNA polymerase II in K562 erythroleukemia cells. It was validated as a high-confidence cis-regulatory element for the BBS12 (Bardet-Biedl syndrome 12), FGF2 (fibroblast growth factor 2) and SPATA5 (spermatogenesis associated 5) genes on chromosome 4 based on mu
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