SREBF1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolSREBF1
Namesterol regulatory element binding transcription factor 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transc

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This is an externally resolved entity

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