gene

SS18L1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about SS18L1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for SS18L1 (CREST) (SS18L1)

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🧬 Gene Info

Gene Symbol	SS18L1
Full Name	SS18L1 (CREST) (SS18L1)
Aliases	CREST
Protein Type	Gene
Function	SS18L1 (also known as CREST) is a transcriptional coactivator that plays important roles in neuronal development and synaptic plasticity.
Primary Expression	neuronal t - Brain Regions: Highest expression in: - Cerebral cortex (layer V pyramidal neurons) - Hippocampus (CA1-CA3 pyramidal cells) - C
Subcellular Localization	**: Nuclear, with activity-dependent translocation
UniProt ID	Q9Y5W2
GeneCards	SS18L1
Human Protein Atlas	SS18L1
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: SS18L1 — AlphaFold Q9Y5W2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SS18L1 (CREST) (SS18L1)

gene · 826 words

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Pathway Diagram

graph TD
    SS18L1["SS18L1"]
    neurodegeneration["neurodegeneration"]
    SS18L1 -->|"implicated_in"| neurodegeneration
    style SS18L1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning SS18L1 in their description or question text

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