Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about STX4A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | STX4A |
| Full Name | Syntaxin 4A |
| Chromosome | 16p13.3 |
| Protein Type | Receptor |
| Function | is a member of the syntaxin family of t-SNARE (target-SNAP receptor) proteins that play essential roles in intracellular vesicle trafficking and membrane fusion. |
| Amino Acids | 289 aa |
| Exons | 9 |
| UniProt ID | P61264 |
| NCBI Gene ID | 6810 |
| Ensembl ID | ENSG00000117415 |
| OMIM | 186591 |
| GeneCards | STX4A |
| Human Protein Atlas | STX4A |
| ER-Golgi trafficking | COPII vesicle fusion with Golgi membranes |
| Endosomal sorting | Multivesicular body formation and lysosomal delivery |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
STX4A["STX4A"]
neurodegeneration["neurodegeneration"]
STX4A -->|"implicated_in"| neurodegeneration
style STX4A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning STX4A in their description or question text
No additional research found