Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SUMF2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Comprehensive review of SUMF2 gene, encoding sulfatase modifying factor 2, a critical cofactor for sulfatase activation with roles in multiple neurodegenerative and metabolic conditions
| Gene Symbol | SUMF2 |
| Full Name | Sulfatase Modifying Factor 2 |
| Chromosome | 7p11.2 |
| Function | is a human gene located on chromosome 7p11. |
| Primary Expression | Ubiquitous - Brain, Liver, Lung, Heart, Muscle |
| Molecular Weight | ~41 kDa |
| Amino Acids | 374 aa |
| UniProt ID | Q8IWA5 |
| NCBI Gene ID | 25873 |
| Ensembl ID | ENSG00000129197 |
| OMIM | 607944 |
| GeneCards | SUMF2 |
| Human Protein Atlas | SUMF2 |
| Alias | FGE-like, SUMF1-like |
| Protein Length | 374 amino acids |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SUMF2["SUMF2"]
neurodegeneration["neurodegeneration"]
SUMF2 -->|"implicated_in"| neurodegeneration
style SUMF2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||