gene

SYNJ2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYNJ2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

SYNJ2 Gene

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	SYNJ2
Full Name	Synaptojanin 2
Chromosome	21q22.11
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	presynaptic terminals, SYNJ2 has distinct cellular and subcellular localization, with important roles in postsynaptic compartments and various membran
Subcellular Localization	, with important roles in postsynaptic compartments and various membrane trafficking pathways relevant to neurodegenerat
Amino Acids	400 aa
UniProt ID	[Q9TQJ7](https://www.uniprot.org/uniprot/Q9TQJ7)
Ensembl ID	ENSG00000199994
GeneCards	SYNJ2
Human Protein Atlas	SYNJ2
Central Sac3 domain	Additional phosphatase domain
C-terminal PRD domain	Proline-rich region for protein-protein interactions
SYNJ2a	Predominantly neuronal
SYNJ2b	More widely expressed, including immune cells
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SYNJ2 Gene

gene · 992 words

→

Pathway Diagram

graph TD
    SYNJ2["SYNJ2"]
    neurodegeneration["neurodegeneration"]
    SYNJ2 -->|"implicated_in"| neurodegeneration
    style SYNJ2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SYNJ2 in their description or question text

No additional research found