gene

SYT9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYT9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

0Outgoing

1Incoming

0Experiments

0Debates

Summary

SYT9 (Synaptotagmin 9) - Calcium sensor for synaptic vesicle exocytosis, critical for neurotransmitter release and implicated in neurodegenerative diseases

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🧬 Gene Info

Gene Symbol	SYT9
Full Name	Synaptotagmin 9
Chromosome	11p15.5
Function	is a member of the synaptotagmin family of calcium-binding proteins that function as sensors for synaptic vesicle exocytosis.
Primary Expression	Brain (cortex, hippocampus, cerebellum), endocrine tissues
Amino Acids	706 aa
UniProt ID	[Q9BQK5](https://www.uniprot.org/uniprot/Q9BQK5)
Ensembl ID	ENSG00000121774
GeneCards	SYT9
Human Protein Atlas	SYT9
Long-term Potentiation (LTP)	SYT9 expression regulated by neuronal activity
Long-term Depression (LTD)	SYT9 degradation during LTD
Homeostatic Plasticity	SYT9 adjusts release probability
Short-term Plasticity	Facilitates depression and facilitation
Associated Diseases	neurodegeneration
Interactions	SYNCRIP
KG Connections	1 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SYT9 Gene

gene · 2776 words

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Pathway Diagram

flowchart TD
    N0["SYT9"]
    N1["SYNCRIP"]
    N1 -->|"interacts with"| N0
    N2["neurodegeneration"]
    N0 -->|"implicated in"| N2

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 protein

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
SYNCRIP	interacts_with	protein	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SYT9 in their description or question text

No additional research found