Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SYT9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
SYT9 (Synaptotagmin 9) - Calcium sensor for synaptic vesicle exocytosis, critical for neurotransmitter release and implicated in neurodegenerative diseases
| Gene Symbol | SYT9 |
| Full Name | Synaptotagmin 9 |
| Chromosome | 11p15.5 |
| Function | is a member of the synaptotagmin family of calcium-binding proteins that function as sensors for synaptic vesicle exocytosis. |
| Primary Expression | Brain (cortex, hippocampus, cerebellum), endocrine tissues |
| Amino Acids | 706 aa |
| UniProt ID | Q9BQK5 |
| NCBI Gene ID | 23244 |
| Ensembl ID | ENSG00000121774 |
| OMIM | 604526 |
| GeneCards | SYT9 |
| Human Protein Atlas | SYT9 |
| Official Symbol | SYT9 |
| Official Full Name | Synaptotagmin 9 |
| Also Known As | Synaptotagmin IX, SytIX |
| Associated Diseases | neurodegeneration |
| Interactions | SYNCRIP |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["SYT9"]
N1["SYNCRIP"]
N1 -->|"interacts with"| N0
N2["neurodegeneration"]
N0 -->|"implicated in"| N2
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 protein| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| SYNCRIP | interacts_with | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||