Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Sulfatide: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Alzheimer's Disease | risk_factor_for | disease | 0.95 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CST | involved_in | enzyme | 0.92 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Myelin Sulfatide Restoration | 0.442 | neurodegeneration | Gene expression changes in aging mouse b |
| Oligodendrocyte-Targeted Myelin Sulfatide Restoration Therap | 0.434 | neurodegeneration | Which cell types show the most significa |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes. [PMID:39865733] | Küçükali F, Hill E, Watzeels T, Hummeric | Brain | 2025 | 0 |
| Long-chain sulfatide enrichment is an actionable metabolic vulnerability in intr [PMID:40268349] | Chen Y, Ballarò R, Sans M, Thege FI, Zuo | Gut | 2025 | 0 |
| A bidirectional link between sulfatide and Alzheimer's disease. [PMID:37972592] | Zimmer VC, Lauer AA, Haupenthal V, Stahl | Cell Chem Biol | 2024 | 0 |
| Sulfatide-selectin signaling in the spinal cord induces mechanical allodynia. [PMID:36528843] | Morita M, Watanabe S, Nomura N, Takano-M | J Neurochem | 2023 | 0 |
| Genetic risk factors for Creutzfeldt-Jakob disease. [PMID:32565065] | Jones E, Mead S | Neurobiol Dis | 2020 | 0 |
| Identification of novel risk loci and causal insights for sporadic Creutzfeldt-J [PMID:32949544] | Jones E, Hummerich H, Viré E, Uphill J, | Lancet Neurol | 2020 | 0 |