Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Synapse Engulfment: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| CX3CL1-CX3CR1 | regulates | mechanism | 0.88 |
| Astrocyte-Synapse Contact | modulates | mechanism | 0.85 |
| SPP1 | causes | gene | 0.70 |
| C3aR | mediates | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Dysregulated microglial glycolysis via HIF1α activation shif | 0.520 | neurodegeneration | Synaptic pruning by microglia in neurode |
Scientific analyses that reference this entity
synaptic biology | 2026-04-07 | 8 hypotheses Top: 0.813
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning Synapse Engulfment in their description or question text
No additional research found