gene

TAAR5

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about TAAR5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for TAAR5 — Trace Amine-Associated Receptor 5

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🧬 Gene Info

Gene Symbol	TAAR5
Full Name	Trace Amine-Associated Receptor 5
Chromosome	6q23.2
Protein Type	Receptor
Function	is a G protein-coupled receptor (GPCR) that belongs to the trace amine receptor family[@liberles2015].
Primary Expression	substantia nigra pars compacta neurons[@panas2020] - Neuroprotection: TAAR5 activation may protect against MPTP toxicity in models - Alpha-synuc
Pathways	MAPK signaling
UniProt ID	Q9Y5Z3
NCBI Gene ID	63814
Ensembl ID	ENSG00000146383
GeneCards	TAAR5
Human Protein Atlas	TAAR5
N-terminal extracellular domain	Ligand binding site for trace amines
Transmembrane domains (TM1-TM7)	Form the ligand-binding pocket
C-terminal intracellular domain	Couples to G proteins
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: TAAR5 — AlphaFold Q9Y5Z3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

TAAR5 — Trace Amine-Associated Receptor 5

gene · 850 words

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Pathway Diagram

graph TD
    TAAR5["TAAR5"]
    neurodegeneration["neurodegeneration"]
    TAAR5 -->|"implicated_in"| neurodegeneration
    style TAAR5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

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Related Research

Hypotheses and analyses mentioning TAAR5 in their description or question text

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