Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TALDO1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | TALDO1 |
| Full Name | Transaldolase |
| Chromosome | 11p15.5 |
| Protein Type | Enzyme |
| Function | encodes a critical enzyme in the non-oxidative branch of the pentose phosphate pathway (PPP), catalyzing the transfer of three-carbon units between sugar phosphates. |
| Primary Expression | Ubiquitous; high in liver, brain |
| Molecular Weight | 37 kDa |
| Amino Acids | 337 aa |
| UniProt ID | P37837 |
| NCBI Gene ID | 6899 |
| Ensembl ID | ENSG00000177189 |
| OMIM | 602335 |
| GeneCards | TALDO1 |
| Human Protein Atlas | TALDO1 |
| N-terminal domain | Substrate binding and catalytic activity |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
TALDO1["TALDO1"]
neurodegeneration["neurodegeneration"]
TALDO1 -->|"implicated_in"| neurodegeneration
style TALDO1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TALDO1 in their description or question text
No additional research found