Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TARDBP (TDP-43) / cryptic splice sites in GABAergic transcripts (DLGAP1, KCNQ2, GABRA1): its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| neurodegeneration | promoted: TDP-43 Cryptic Exon–Targeted ASOs to Restore Hippocampal Gamma Oscillations | disease | 0.58 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| TDP-43 Cryptic Exon–Targeted ASOs to Restore Hippocampal Gam | 0.577 | neurodegeneration | RNA binding protein dysregulation across |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-13 | 2 hypotheses Top: 0.664
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||