TPT1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolTPT1
Nametumor protein, translationally-controlled 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is requir

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