gene

TIAL1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TIAL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Incoming

0Experiments

0Debates

Summary

Comprehensive information about TIAL1, an RNA-binding protein involved in stress granule formation, translational regulation, and implicated in amyotrophic lateral sclerosis, frontotemporal dementia, and other neurodegenerative diseases.

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🧬 Gene Info

Gene Symbol	TIAL1
Full Name	TIA1 Cytotoxic Granule Associated RNA Binding Protein Like 1
Aliases	TIA1 Cytotoxic Granule-Associated RNA Binding Protein
Chromosome	10q11.23
Function	encodes a member of the TIA1 family of RNA-binding proteins.
Molecular Weight	46 kDa
Amino Acids	405 aa
Exons	13
UniProt ID	[Q9YKf3](https://www.uniprot.org/uniprot/Q9YKf3)
Ensembl ID	ENSG00000173113
GeneCards	TIAL1
Human Protein Atlas	TIAL1
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

TIAL1 — TIA1 Cytotoxic Granule Associated RNA Binding Protein Like 1

gene · 2901 words

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TIAL1 Protein (TIA1 Cytotoxic Granule-Associated RNA Binding Protein)

protein · 634 words

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Pathway Diagram

graph TD
    TIAL1["TIAL1"]
    neurodegeneration["neurodegeneration"]
    TIAL1 -->|"implicated_in"| neurodegeneration
    style TIAL1 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
    style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TIAL1 in their description or question text

No additional research found