TLR5

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolTLR5
Nametoll like receptor 5
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn

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