gene

TMEM163

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TMEM163: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

TMEM163 (also known as MDSynapse) encodes a transmembrane protein implicated in zinc transport, synaptic function, and neurodegenerative disease susceptibility

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🧬 Gene Info

Gene Symbol	TMEM163
Full Name	Transmembrane Protein 163
Aliases	also known as MDSynapse
Chromosome	2p16.3
Protein Type	Transporter
Function	encodes a membrane protein initially identified as a synapse-associated protein.
Molecular Weight	45 kDa
Exons	5
GeneCards	TMEM163
Human Protein Atlas	TMEM163
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    TMEM163["TMEM163"]
    neurodegeneration["neurodegeneration"]
    TMEM163 -->|"implicated_in"| neurodegeneration
    style TMEM163 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TMEM163 in their description or question text

No additional research found