gene

TMEM237

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about TMEM237: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for TMEM237 — Transmembrane Protein 237

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🧬 Gene Info

Gene Symbol	TMEM237
Full Name	Transmembrane Protein 237
Chromosome	2q33.3
Function	TMEM237 is a multipass transmembrane protein localized to the endoplasmic reticulum (ER).
Subcellular Localization	the endoplasmic reticulum (ER). It is involved in:
Amino Acids	479 aa
Pathways	signaling: - Modulates ER calcium store release
UniProt ID	Q9H6K1
NCBI Gene ID	130814
Ensembl ID	ENSG00000135902
OMIM	614215
GeneCards	TMEM237
Human Protein Atlas	TMEM237
N-terminal cytosolic domain	Contains potential phosphorylation sites
Multiple transmembrane helices	Spanning the ER membrane
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: TMEM237 — AlphaFold Q9H6K1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

TMEM237 — Transmembrane Protein 237

gene · 882 words

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Pathway Diagram

graph TD
    TMEM237["TMEM237"]
    neurodegeneration["neurodegeneration"]
    TMEM237 -->|"implicated_in"| neurodegeneration
    style TMEM237 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning TMEM237 in their description or question text

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