gene

TMEM55A

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about TMEM55A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	TMEM55A
Full Name	Transmembrane Protein 55A
Chromosome	8q13.1 (NC_000008.11: 90993802..91040859)
Function	is a gene on chromosome 8q13.
Primary Expression	Brain, Substantia Nigra, lysosomal compartments
Subcellular Localization	endolysosomal membranes where it plays a critical role in regulating phosphatidylinositol (PI) signaling and lysosomal f
Amino Acids	257 aa
UniProt ID	Q8N4L2
NCBI Gene ID	55529
Ensembl ID	ENSG00000149547
OMIM	609864
GeneCards	TMEM55A
Human Protein Atlas	TMEM55A
Genomic span	~47 kb
RefSeq transcript	NM_018710.3 (2,759 nt)
Databases	GeneCards HPA STRING

🔮 Predicted Structure: TMEM55A — AlphaFold Q8N4L2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

TMEM55A — Transmembrane Protein 55A

gene · 882 words

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Pathway Diagram

graph TD
    TMEM55A["TMEM55A"]
    neurodegeneration["neurodegeneration"]
    TMEM55A -->|"implicated_in"| neurodegeneration
    style TMEM55A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning TMEM55A in their description or question text

No additional research found