Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TMEM71: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | TMEM71 |
| Full Name | Transmembrane Protein 71 |
| Chromosome | 15q21.3 |
| Function | TMEM71 is a multipass transmembrane protein localized to the plasma membrane and intracellular vesicles. |
| Subcellular Localization | the plasma membrane and intracellular vesicles. Its exact function is not well characterized but may be involved in: |
| Amino Acids | 503 aa |
| Pathways | MAPK pathway |
| UniProt ID | Q8N6M3 |
| NCBI Gene ID | 137886 |
| Ensembl ID | ENSG00000149691 |
| OMIM | 616785 |
| GeneCards | TMEM71 |
| Human Protein Atlas | TMEM71 |
| Multiple transmembrane domains | 7-9 predicted transmembrane helices |
| N-terminal signal peptide | For membrane insertion |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
TMEM71["TMEM71"]
neurodegeneration["neurodegeneration"]
TMEM71 -->|"implicated_in"| neurodegeneration
style TMEM71 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TMEM71 in their description or question text
No additional research found