enzyme

TMPRSS2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TMPRSS2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

17Connections
0Hypotheses
0Analyses
9Outgoing
8Incoming

No summary available yet. View on Wiki →

🔬 Protein Info
Gene SymbolTMPRSS2
PathwaysSars-Cov-2 Infection
GeneCardsTMPRSS2
Human Protein AtlasTMPRSS2
Associated DiseasesSARS-CoV-2
InteractionsACE2, FCGRT, SARS
KG Connections17 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (2)

Knowledge base pages for this entity

Post-Acute Viral Reservoir Hypothesis in Parkinson's Disease

hypothesis · 2262 words

AR Protein

protein · 838 words

Pathway Diagram

graph TD
    TMPRSS2["TMPRSS2"] -->|"involved in"| SARS_CoV_2["SARS-CoV-2"]
    style SARS_CoV_2 fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    TMPRSS2["TMPRSS2"] -->|"involved in"| Sars_Cov_2_Infection["Sars-Cov-2 Infection"]
    style Sars_Cov_2_Infection fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    TMPRSS2["TMPRSS2"] -->|"protects against"| ALS["ALS"]
    style ALS fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    TMPRSS2["TMPRSS2"] -->|"protects against"| AND["AND"]
    style AND fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    TMPRSS2["TMPRSS2"] -->|"protects against"| FCGRT["FCGRT"]
    style FCGRT fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    TMPRSS2["TMPRSS2"] -->|"protects against"| Rb["Rb"]
    style Rb fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    ACE2["ACE2"] -->|"protects against"| TMPRSS2["TMPRSS2"]
    style ACE2 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    FCGRT_1["FCGRT"] -->|"protects against"| TMPRSS2["TMPRSS2"]
    style FCGRT_1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    SARS["SARS"] -->|"interacts"| TMPRSS2["TMPRSS2"]
    style SARS fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    style TMPRSS2 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (9)

TargetRelationTypeStr
SARS-CoV-2associated_withentity0.90
Sars-Cov-2 Infectioninvolved_inprocess0.90
SARS-CoV-2activatesentity0.80
ALSprotects_againstdisease0.65
Alsprotects_againstdisease0.65

Incoming (8)

SourceRelationTypeStr
ACE2protects_againstgene0.60
FCGRTprotects_againstgene0.60
ACE2interacts_withgene0.60
FCGRTinteracts_withgene0.60
SARSinteracts_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found