TNFSF10

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolTNFSF10
NameTNF superfamily member 10
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activit

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This is an externally resolved entity

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