TOLLIP

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolTOLLIP
Nametoll interacting protein
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016].

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This is an externally resolved entity

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