TPM2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolTPM2
Nametropomyosin 2
Typeprotein-coding
Sourcemygene

Summary

This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].

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