Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TREM2 p.Q33X mutation: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| lysosomal dysfunction | causes | phenotype | 0.90 |
| Nasu-Hakola disease | causes | disease | 0.90 |
| cholesterol genes | inhibits | gene | 0.80 |
| lipid droplets | inhibits | phenotype | 0.80 |
| benchmark_ot_ad_answer_key:TREM2 P.Q33X MUTATION | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:TREM2 P.Q33X MUTATION | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||