gene

TRIM17

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about TRIM17: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

TRIM17 (Tripartite Motif Containing 17) — RBCC E3 ubiquitin ligase regulating neuronal apoptosis, spinocerebellar ataxia, and Huntington's disease pathology

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🧬 Gene Info

Gene Symbol	TRIM17
Aliases	Tripartite Motif Containing 17
Chromosome	1q42.13
Protein Type	Gene
Function	is a member of the tripartite motif (TRIM) family of E3 ubiquitin ligases.
Primary Expression	the brain, with high expression in the cerebellum, hippocampus, and cerebral cortex, regions critically involved in movement coordination and cognitiv
Molecular Weight	52 kDa
Amino Acids	462 aa
Exons	3
GeneCards	TRIM17
Human Protein Atlas	TRIM17
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

TRIM17 Gene

gene · 2097 words

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Pathway Diagram

graph TD
    TRIM17["TRIM17"]
    neurodegeneration["neurodegeneration"]
    TRIM17 -->|"implicated_in"| neurodegeneration
    style TRIM17 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning TRIM17 in their description or question text

No additional research found