TRPM1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolTRPM1
Nametransient receptor potential cation channel subfamily M member 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognost

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