TRPV4

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolTRPV4
Nametransient receptor potential cation channel subfamily V member 4
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding diffe

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