Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TUBB6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | TUBB6 |
| Full Name | Tubulin Beta 6 Class V |
| Chromosome | 18p11.21 |
| Function | TUBB6 is a beta-tubulin isotype involved in microtubule polymerization. |
| Primary Expression | neurons and glial cells and contributes to cytoskeletal stability |
| UniProt ID | [Q9BUF5](https://www.uniprot.org/uniprotkb/Q9BUF5/entry) |
| GeneCards | TUBB6 |
| Human Protein Atlas | TUBB6 |
| Alpha-tubulins (TUBA1A, TUBA1B) | Binding partners that form functional microtubule units |
| Microtubule-associated proteins | Interact with TUBB6-containing microtubules |
| Molecular motors | Kinesin and dynein depend on TUBB6-containing tracks |
| Associated Diseases | Peripheral neuropathy, lissencephaly |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
TUBB6["TUBB6"]
neurodegeneration["neurodegeneration"]
TUBB6 -->|"implicated_in"| neurodegeneration
style TUBB6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TUBB6 in their description or question text
No additional research found