TXNRD1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolTXNRD1
Namethioredoxin reductase 1
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed, cytosolic form of TrxR, which functions as a homodimer containing FAD, and selenocysteine

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