Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TYNDASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
TYNDASE (Tyndall/C12orf45) is a gene implicated in ALS and other neurodegenerative diseases, encoding a protein involved in neuronal development and cellular stress responses.
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| Gene Symbol | TYNDASE |
| Full Name | Tyndall |
| Aliases | Tyndall/C12orf45 |
| Chromosome | 5p15.33 |
| Protein Type | Uncharacterized protein |
| Function | encodes a protein involved in various cellular processes relevant to neuronal survival and function, including neuronal development, synaptic formation, cytoskeletal dynamics, and cellular stress r... |
| Primary Expression | Brain, Spinal cord, Lung, Testis |
| UniProt ID | Q9H5Y2 |
| NCBI Gene ID | 9047 |
| Ensembl ID | ENSG00000165682 |
| OMIM | 610035 |
| GeneCards | TYNDASE |
| Human Protein Atlas | TYNDASE |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
TYNDASE["TYNDASE"]
neurodegeneration["neurodegeneration"]
TYNDASE -->|"implicated_in"| neurodegeneration
style TYNDASE fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TYNDASE in their description or question text
No additional research found